Doing South America.

A  few suggestions amongst millions of choices!

Brasil
Too many places I would suggest visiting but of course one simply must:
Rio de Janeiro (see link below for my top tips on Rio) - this is ever changing and I'm not great at keeping it updated but some are classic that never really change!
http://wings-unclipped.blogspot.com/2010/07/o-rio-de-janeiro-continua-lindo.html


Argentina
Buenos Aires (see link below for my top tips on BA)
http://wings-unclipped.blogspot.com/2010/07/buenos-aires-in-nutshell.html

Patagonia- go down to the south and see the glaciers

Get to Salta where it all gets very rural.. too brilliant for words. From here you get the bus and start travelling north!!! I definitely recommend a visit to the Andes- get on a raft and back in with nature.

Bolivia

Top tip: make sure you take altitude tablets. Badge got altitude sickness when we were out there and I tell you camping in a Bolivian hospital is the WORST experience in the world! The border is a dodgy place, you wouldn't want to get stuck there like I did.

Salt Lakes

La Paz

When in La Paz make sure you do the World's Most Dangerous bike ride with "gravity" http://www.gravitybolivia.com/index.php?mod=tempview1&id=1251406369
Whether you're a cycle nut or not it's worth every penny of this for the adrenaline you get and the view around you. 8 hours of biking down dirt tracks surrounded by jungle and cliffs. Stay the night in the hotel that you have dinner in- really lovely!

Lake Titicaca

Lake Titicaca- a suggestion is to hire an old motorbike and explore the lakes.Spend a night in Copacabana. Pop to the irish man's little place by the water, order his local delicatessen.

Spend some quality time with a Bolivian family - get with it, try there clothes, there food, no electricity. indulge on fresh air and live the simple life for a while. 

Visit isla del sol.

Peru - Machu Pitchu
Top tip: However tired you are you simply MUST MUST climb up to WAYNA PITCHU as the view from the top is by far the most incredible!!! People spend days getting to machu only to miss out on this extra climb. Dont let sore legs and lungs defeat you. climb. Cusco for a night out.

Are you a jungle lover. do the Amazon.

If time is limited... From Cusco buy a flight to Puerto Maldonado. Not something for the faint hearted - sleep in huts, wash amongst piranhas and alligators, you will see tarantulas everywhere- fish at dawn, go out in a canoe at night - explore. Silence. creepy crawlers. Amazing.